
Lactuca virosa
Wild Lettuce
Asteraceae
At a Glance
- Common name
- Wild Lettuce
- Scientific name
- Lactuca virosa
- Family
- Asteraceae
- Region
- Europe / Mediterranean
- Plant part
- Leaves, Milky latex (lactucarium)
- Caffeine
- Caffeine Free
- Evidence
- Insufficient
- Safety review
- Safety information on file
Safety & Cautions
Safety information on fileBotanical Description
A tall biennial with large lobed blue-green leaves clasping a hollow stem that exudes a milky latex, and a loose pyramidal cluster of small pale-yellow composite flowers; the leaves and latex are used.
Also known as: Bitter Lettuce, Lactucarium, Opium Lettuce
Historical Background
Wild lettuce has been a European and Mediterranean folk sedative for centuries, its milky latex ('lactucarium') prized as 'lettuce opium' for pain and sleep. The leaves brew a mild, calming, caffeine-free cup, while the concentrated latex is far stronger and historically used cautiously.
Earliest recorded uses: European and Mediterranean traditions for centuries; a mild sedative and pain herb ('lettuce opium').
Traditional preparations:
- Leaf infusion
- Calming evening tea
- Practitioner-guided latex use
Traditional Uses
These uses document historical traditions and do not imply proven effectiveness.
European Folk Traditions
Mild folk sedative and pain herb.
Modern Herbalism
Calming caffeine-free cup (leaves only).
Flavor & Aroma
Aroma: Mild, green, slightly bitter, milky
Tea Preparation
Modern Evidence
Wild lettuce has a tradition as a mild sedative and pain herb; preclinical work suggests sedative activity from lactucarium (lactucin). Clinical evidence is insufficient; it is not a treatment for insomnia, pain, anxiety, or any disease, and its concentrated latex warrants cautious, practitioner-guided use.
Evidence levels describe the state of research for the traditional use discussed here, not a recommendation. Historical use does not imply effectiveness.
Related Herbs
Entry last updated August 4, 2026






