St. John's Wort

At a Glance

Common name

St. John's Wort

Scientific name

Hypericum perforatum

Family

Hypericaceae

Region

Europe

Plant part

Aerial parts, Flowering tops

Caffeine

Caffeine Free

Evidence

Moderate

Safety review

Safety information on file

Botanical Description

An erect perennial 30-80 cm tall with opposite oval leaves held to light showing translucent oil glands, and flat-topped clusters of bright yellow five-petalled flowers with many bushy stamens dotted with black glands.

Also known as: Hypericum, Klamath Weed, Tipton's Weed

Historical Background

St. John's wort has been a revered European healing herb since antiquity, named for the feast of St. John the Baptist near which it blooms. Its golden, oil-dotted flowers were infused in oil for a red healing salve, and the plant has long been used to lift the spirits. Today it is among the most studied herbal mood remedies.

Earliest recorded uses: Greek and medieval European medicine; named for St. John the Baptist (blooms near his feast day); a traditional mood herb.

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Flavor & Aroma

Aroma: Herbal, warm, balsamic, slightly bitter

Tea Preparation

Modern Evidence

St. John's wort has the strongest clinical evidence of most herbs for mild-to-moderate low mood, with trials comparing it to standard antidepressants. However, it has clinically significant drug interactions that can reduce the effectiveness of many medications. It is not a substitute for professional care and must be discussed with a clinician.

Evidence levels describe the state of research for the traditional use discussed here, not a recommendation. Historical use does not imply effectiveness.