Educational reference only · Not medical advice · Always consult a qualified healthcare professional
Seville Orange

Citrus aurantium

Seville Orange

Rutaceae

Evidence: LimitedCaffeine Free (but synephrine is stimulant) Mediterranean / AsiaDigestive ComfortRelaxationAntioxidant Traditions
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Identity

Common Name
Seville Orange
Scientific Name
Citrus aurantium
Botanical Family
Rutaceae
Native Region
Southeast Asia
Cultivation Regions
Mediterranean, Asia, warm temperate regions
Plant Parts Used
Peel, Flowers (neroli), Leaves
Synonyms
Bitter Orange, Sour Orange, Zhi Shi
Caffeine Level
Caffeine Free (but synephrine is stimulant)

An evergreen tree with glossy ovate leaves, fragrant white orange-blossom flowers, and a round bumpy orange fruit; the leaves, flowers (neroli), and peel are used.

Historical Background

Seville (bitter) orange has been a Mediterranean and Asian treasure for centuries, its sour fruit prized for marmalade, its fragrant blossom distilled into neroli, and its leaves and peel brewed into a bitter digestive tea. Traditional Chinese practice uses the immature fruit (zhi shi) for digestion.

Earliest recorded uses: Mediterranean and Asian traditions for centuries; a bitter orange for peel, blossom (neroli), and leaf.

Traditional preparations:

  • Peel decoction
  • Neroli blossom infusion
  • Bitter digestive tea

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Chinese Traditions

Bitter digestive peel (zhi shi) and neroli blossom.

Mediterranean Traditions

Bitter digestive and aromatic cup.

Flavor & Aroma

CitrusBitter-orangeFloralSlightly Spicy

Aroma: Citrus, bitter-orange, floral, slightly spicy

Tea Information

Suitable for Tea
Yes
Preparation Methods
Peel decoction, Blossom infusion (neroli), Leaf tea
Steeping Temperature
200 F (93 C)
Steeping Time
5-8 minutes
Recommended Vessel
Teapot or saucepan
Blends Well With
Green Tea, Mint, Ginger, Honey, Rose Hips
200 F (93 C) 5-8 minutes

Safety & Cautions

Contraindications
Contains synephrine - avoid with hypertension, heart disease, arrhythmia, glaucoma, and with MAOIs, caffeine, and stimulants; avoid medicinal doses in pregnancy; limit in anxiety and insomnia; discontinue before surgery.
Drug Interactions
Synephrine interacts with MAOIs, caffeine, decongestants, blood-pressure, and heart medications - consult a clinician.
Pregnancy
Avoid medicinal doses; synephrine stimulant - consult a clinician.
Breastfeeding
Avoid medicinal doses; synephrine stimulant - consult a clinician.
Children
Not recommended for regular use by children; synephrine stimulant.
Allergies
Possible in those sensitive to Rutaceae; citrus allergy possible.
Known Adverse Effects
May cause jitteriness, anxiety, palpitations, headache, insomnia, or elevated blood pressure from synephrine; high doses may affect heart rhythm; rare allergic reactions.

Research Summary

Evidence Level: Limited

Seville orange has a tradition as a bitter digestive, and its blossom (neroli) as a calming aroma; the peel contains synephrine, a stimulant with cardiovascular concerns at high doses. Clinical evidence is mixed; it is not a treatment for obesity, indigestion, anxiety, or any disease, and stimulant-containing products warrant caution.

Evidence levels reflect the currently available scientific literature and may change as new research emerges. Where evidence is limited or conflicting, this is stated plainly.

References & Sources

References & Sources

  1. EMA HMPC · Aurantii pericarpium monograph (2014)
  2. PubMed · Citrus aurantium synephrine review (2019)

Related Herbs

Soothing Brews

An educational encyclopedia preserving the history, traditions, and modern evidence behind herbs used in teas and infusions. Inspired by antique botanical manuscripts.

Steeped in tradition, grounded in honesty.

Please Note

This is an educational reference, not a medical resource. Historical use does not imply effectiveness. Natural does not always mean safe. Consult a qualified healthcare professional before using herbs, especially if pregnant, nursing, or taking medications.

© 2026 Soothing Brews · For educational purposes only.

Preferred sources: NIH ODS · NCCIH · MSK Herbs · PubMed · WHO · EMA · German Commission E · Cochrane