Educational reference only · Not medical advice
Botanical illustration of Schisandra

Schisandra chinensis

Schisandra

Schisandraceae

Evidence: LimitedCaffeine Free ChinaSafety information on file
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At a Glance

Common name
Schisandra
Scientific name
Schisandra chinensis
Family
Schisandraceae
Region
China
Plant part
Berries
Caffeine
Caffeine Free
Evidence
Limited
Safety review
Safety information on file

Safety & Cautions

Safety information on file
Contraindications
Avoid in pregnancy (traditional contraindication), peptic ulcers, and epilepsy; may affect liver at high doses.
Drug interactions
May interact with medications metabolized by the liver (CYP enzymes) and anticoagulants; consult a clinician.
Pregnancy
Avoid; traditionally contraindicated.
Children
Not recommended as a tonic.
Allergies
Rare.
Known adverse effects
Generally well tolerated; mild GI upset, heartburn, or appetite loss reported.

Botanical Description

A deciduous woody vine with oval leaves and dangling clusters of small red berries whose five tastes — sweet, sour, salty, bitter, and pungent — give it its Chinese name wu wei zi ('five-flavor seed').

Also known as: Five-Flavor Berry, Wu Wei Zi

Historical Background

Schisandra is a revered TCM tonic — classified among the superior herbs in the Shennong Ben Cao Jing (~100 CE) — used for qi, 'calming the spirit,' supporting the liver, and as an adaptogen. In Russia it was studied in the 20th century as an adaptogen for stamina and endurance.

Earliest recorded uses: Shennong Ben Cao Jing (~1st c. CE) lists it among superior, non-toxic tonics.

Cultural significance: Schisandra's five tastes in one berry are said to nourish the five yin organs in TCM — a botanical emblem of balance, and one of the herbs that bridged TCM and Soviet adaptogen research.

Traditional preparations:

  • Berry decoction
  • Berry infusion
  • Powder

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Traditional Chinese Medicine

Tonic for qi, liver support, calming the spirit; wu wei zi.

Modern Herbalism

Adaptogen for stress, endurance, and focus.

Flavor & Aroma

SweetSourBitterSaltyPungent

Aroma: Tart, fruity, complex

Tea Preparation

Preparation methods
Decoction, Infusion
Steeping temperature
200°F (93°C)
Steeping time
10–12 minutes (decoction)
Recommended vessel
Covered teapot
Blends well with
Green Tea, Goji, Ginger, Rose
200°F (93°C) 10–12 minutes (decoction)

Modern Evidence

Evidence level: Limited

Schisandra has a long TCM adaptogen tradition and has been studied in small trials for liver support, endurance, and cognition, but evidence is limited and studies are small and often of poor quality. It is not a treatment for liver disease or fatigue disorders.

Evidence levels describe the state of research for the traditional use discussed here, not a recommendation. Historical use does not imply effectiveness.

References & Sources

  1. NCCIH · Schisandra (2023)
  2. WHO · WHO Monographs (Schisandrae chinensis fructus) (2009)

Entry last updated August 4, 2026

Soothing Brews

An educational encyclopedia preserving the history, traditions, and modern evidence behind herbs used in teas and infusions. Inspired by antique botanical manuscripts.

Steeped in tradition, grounded in honesty.

Please Note

This is an educational reference, not a medical resource. Historical use does not imply effectiveness. Natural does not always mean safe. Consult a qualified healthcare professional before using herbs, especially if pregnant, nursing, or taking medications.

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Preferred sources: NIH ODS · NCCIH · MSK Herbs · PubMed · WHO · EMA · German Commission E · Cochrane