Oregon Grape

At a Glance

Common name

Oregon Grape

Scientific name

Mahonia aquifolium

Family

Berberidaceae

Region

Pacific Northwest

Plant part

Root, Root bark

Caffeine

Caffeine Free

Evidence

Limited

Safety review

Safety information on file

Botanical Description

An evergreen shrub with glossy spiny holly-like pinnate green leaves, clusters of small bright yellow flowers, and dangling clusters of round blue-purple grape-like berries; the root and root bark are used (sometimes the leaf).

Also known as: Oregon Grape Holly, Mountain Grape, Holly-Leaved Barberry

Historical Background

Oregon grape has been an Indigenous Pacific Northwest medicine for centuries, its bright yellow berberine-rich root used much like goldenseal for skin, liver, and infection. A sustainable native alternative to goldenseal, it remains a potent, bitter, practitioner-guided herb.

Earliest recorded uses: Indigenous Pacific Northwest traditions for centuries; a bitter yellow root for skin, liver, and infection.

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Flavor & Aroma

Aroma: Bitter, tart, slightly fruity, earthy

Tea Preparation

Modern Evidence

Oregon grape has a tradition as a bitter liver, skin, and antimicrobial root; berberine shows antimicrobial and anti-inflammatory activity in vitro, and some topical use for psoriasis. Clinical evidence for internal tea is limited; it is not a treatment for psoriasis, liver disease, infection, or any disease, and its strong alkaloids warrant short-term, cautious use.

Evidence levels describe the state of research for the traditional use discussed here, not a recommendation. Historical use does not imply effectiveness.