Educational reference only · Not medical advice
Botanical illustration of Neem

Azadirachta indica

Neem

Meliaceae

Evidence: InsufficientCaffeine Free South AsiaSafety information on file
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At a Glance

Common name
Neem
Scientific name
Azadirachta indica
Family
Meliaceae
Region
South Asia
Plant part
Leaves, Bark
Caffeine
Caffeine Free
Evidence
Insufficient
Safety review
Safety information on file

Safety & Cautions

Safety information on file
Contraindications
Generally safe in small food/tea amounts but very bitter; avoid medicinal doses in pregnancy (may reduce fertility and stimulate immune); avoid with blood-sugar, immunosuppressant, and kidney medications; discontinue before surgery; avoid long-term high-dose use.
Drug interactions
May lower blood sugar; may affect immunosuppressants and kidney-metabolized drugs - consult a clinician before use.
Pregnancy
Avoid; may reduce fertility and has immune effects.
Breastfeeding
Avoid; limited safety data and strong compounds.
Children
Not recommended for regular use by children; very bitter and limited safety data.
Allergies
Possible in those sensitive to Meliaceae; rare.
Known adverse effects
Generally well tolerated in small amounts; high doses or long-term use may cause GI upset, liver strain, or kidney irritation; very bitter; rare allergic reactions.

Botanical Description

A tropical evergreen tree with pinnate compound glossy deep-green serrated leaflets and small sprays of tiny white fragrant flowers; the leaves and bark are used.

Also known as: Margosa, Indian Lilac, Nimba

Historical Background

Neem has been an Ayurvedic 'village pharmacy' for millennia, its bitter leaves and bark used for skin, immune, fever, and cleansing traditions. Revered across South Asia, it is rarely a casual sip but features in practitioner-guided Ayurvedic teas and bitter tonics.

Earliest recorded uses: Ayurvedic traditions for millennia; a bitter 'village pharmacy' tree for skin, immune, and fever traditions.

Traditional preparations:

  • Small-dose leaf infusion
  • Bitter Ayurvedic tonic
  • Practitioner-guided cup

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Ayurvedic Traditions

Bitter 'village pharmacy' for skin, immune, and fever.

Modern Herbalism

Bitter antimicrobial and cleansing cup.

Flavor & Aroma

BitterStrongSulfur-likeHerbaceous

Aroma: Bitter, strong, sulfur-like, herbaceous

Tea Preparation

Preparation methods
Infusion (small dose), Practitioner-guided use
Steeping temperature
200 F (93 C)
Steeping time
3-5 minutes
Recommended vessel
Teapot
Blends well with
Tulsi, Ginger, Turmeric, Honey, Peppermint
200 F (93 C) 3-5 minutes

Modern Evidence

Evidence level: Insufficient

Neem has a tradition as a bitter antimicrobial, skin, immune, and blood-sugar herb; preclinical work shows broad antimicrobial, anti-inflammatory, and modest glucose-modulating activity. Clinical evidence is insufficient; it is not a treatment for infection, skin disease, diabetes, malaria, or any disease, and its strong, bitter compounds warrant short, cautious use.

Evidence levels describe the state of research for the traditional use discussed here, not a recommendation. Historical use does not imply effectiveness.

References & Sources

  1. EMA HMPC · Azadirachta assessment (2015)
  2. PubMed · Azadirachta indica review (2019)

Entry last updated August 4, 2026

Soothing Brews

An educational encyclopedia preserving the history, traditions, and modern evidence behind herbs used in teas and infusions. Inspired by antique botanical manuscripts.

Steeped in tradition, grounded in honesty.

Please Note

This is an educational reference, not a medical resource. Historical use does not imply effectiveness. Natural does not always mean safe. Consult a qualified healthcare professional before using herbs, especially if pregnant, nursing, or taking medications.

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Preferred sources: NIH ODS · NCCIH · MSK Herbs · PubMed · WHO · EMA · German Commission E · Cochrane