Educational reference only · Not medical advice
Botanical illustration of Jiaogulan

Gynostemma pentaphyllum

Jiaogulan

Cucurbitaceae

Evidence: LimitedCaffeine Free ChinaSafety information on file
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At a Glance

Common name
Jiaogulan
Scientific name
Gynostemma pentaphyllum
Family
Cucurbitaceae
Region
China
Plant part
Leaves
Caffeine
Caffeine Free
Evidence
Limited
Safety review
Safety information on file

Safety & Cautions

Safety information on file
Contraindications
Generally very safe in tea amounts; avoid in autoimmune disease, and with immunosuppressants; caution with antidiabetic and antihypertensive drugs; discontinue before surgery.
Drug interactions
May lower blood sugar and blood pressure and may enhance bleeding with anticoagulants; may modulate immunosuppressants; consult a clinician.
Pregnancy
Generally regarded as safe in tea amounts.
Children
Mild infusions acceptable in small amounts.
Allergies
Possible in those sensitive to Cucurbitaceae; rare.
Known adverse effects
Generally very well tolerated; may cause mild GI upset or, rarely, nausea or allergic reactions.

Botanical Description

A slender climbing vine with compound leaves of five oval serrated leaflets arranged like a hand, and trailing clusters of small greenish-yellow five-petalled flowers; the leaves are the part used.

Also known as: Immortality Herb, Southern Ginseng, Xiancao

Historical Background

Jiaogulan ('immortality herb') has been a folk tea of southern China's mountainous Guizhou for centuries, drunk for daily vitality and longevity. Its five-leafed vine brews a gentle, sweet cup, earning it the modern nickname 'southern ginseng.'

Earliest recorded uses: Used in southern Chinese folk medicine for centuries; 'immortality herb' of mountainous Guizhou; popularized in modern times as a ginseng-like adaptogen.

Traditional preparations:

  • Leaf infusion
  • Daily vitality tea
  • Adaptogen blend with jujube

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Traditional Chinese Medicine

Daily vitality and longevity tea; 'immortality herb' of Guizhou.

Modern Herbalism

Adaptogen and antioxidant tea.

Flavor & Aroma

MildSlightly SweetGreenBeany

Aroma: Mild, slightly sweet, green, beany

Tea Preparation

Preparation methods
Infusion
Steeping temperature
190°F (88°C)
Steeping time
5-7 minutes (re-steepable)
Recommended vessel
Teapot
Blends well with
Green Tea, Jujube, Ginseng, Honey, Chrysanthemum
190°F (88°C) 5-7 minutes (re-steepable)

Modern Evidence

Evidence level: Limited

Jiaogulan has a tradition as an adaptogen and antioxidant tea. Clinical evidence is limited; preclinical work shows antioxidant and metabolic activity, but it is not a treatment for diabetes, cholesterol, fatigue, or any disease.

Evidence levels describe the state of research for the traditional use discussed here, not a recommendation. Historical use does not imply effectiveness.

References & Sources

  1. PubMed · Gynostemma pentaphyllum review (2019)
  2. EMA HMPC · Gynostemma assessment (2017)

Entry last updated August 4, 2026

Soothing Brews

An educational encyclopedia preserving the history, traditions, and modern evidence behind herbs used in teas and infusions. Inspired by antique botanical manuscripts.

Steeped in tradition, grounded in honesty.

Please Note

This is an educational reference, not a medical resource. Historical use does not imply effectiveness. Natural does not always mean safe. Consult a qualified healthcare professional before using herbs, especially if pregnant, nursing, or taking medications.

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Preferred sources: NIH ODS · NCCIH · MSK Herbs · PubMed · WHO · EMA · German Commission E · Cochrane