Educational reference only · Not medical advice
Botanical illustration of Bupleurum

Bupleurum chinense

Bupleurum

Apiaceae

Evidence: LimitedCaffeine Free ChinaSafety information on file
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At a Glance

Common name
Bupleurum
Scientific name
Bupleurum chinense
Family
Apiaceae
Region
China
Plant part
Root
Caffeine
Caffeine Free
Evidence
Limited
Safety review
Safety information on file

Safety & Cautions

Safety information on file
Contraindications
Avoid in pregnancy and breastfeeding; avoid in autoimmune disease and with immunosuppressive or corticosteroid therapy without professional supervision; discontinue before surgery; may affect liver-metabolized drugs.
Drug interactions
May modulate immune-suppressive and corticosteroid effects; may affect liver-metabolized drugs; consult a clinician.
Pregnancy
Avoid; safety in pregnancy and breastfeeding has not been established. Traditional use does not establish safety.
Breastfeeding
Avoid; safety in breastfeeding has not been established.
Children
Not recommended for children without professional guidance.
Allergies
Possible in those sensitive to Apiaceae; rare.
Known adverse effects
May cause gastrointestinal upset or, rarely, allergic reactions. Liver effects have been reported with some Bupleurum preparations; safety requires professional supervision.

Botanical Description

An erect perennial with alternate narrow lance-shaped leaves that clasp the stem, and small clusters of yellow flowers in umbels; the long thin tapering root is the part used in classic TCM formulas.

Also known as: Chai Hu, Thorow Wax, Hare's Ear

Historical Background

Bupleurum (chai hu) has been the chief herb of Traditional Chinese Medicine's 'harmonizing' formulas for over 2,000 years, used to soothe the Liver Qi and clear alternating heat-and-cold patterns. Its slender root is a pillar of classic formulas like Xiao Chai Hu Tang.

Earliest recorded uses: Used in TCM for over 2,000 years; the lead herb of the classic Harmonizing formula Xiao Chai Hu Tang.

Traditional preparations:

  • Root decoction
  • Harmonizing formula (Xiao Chai Hu Tang)
  • Liver-support blend with licorice

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Traditional Chinese Medicine

Harmonizes Shaoyang, soothes Liver Qi; lead herb of harmonizing formulas.

Modern Herbalism

Liver-support and digestive adaptogen tea.

Flavor & Aroma

MildSlightly SweetBittersweetGreen

Aroma: Mild, slightly sweet, bittersweet, green

Tea Preparation

Preparation methods
Decoction
Steeping temperature
200°F (93°C)
Steeping time
15-20 minutes simmer (decoction)
Recommended vessel
Saucepan (decoction)
Blends well with
Astragalus, Jujube, Goji Berry, Ginger, Licorice Root
200°F (93°C) 15-20 minutes simmer (decoction)

Modern Evidence

Evidence level: Limited

Bupleurum has a long TCM tradition as a harmonizing liver herb. Clinical evidence is limited; preclinical work shows hepatoprotective and anti-inflammatory activity, but it is not a treatment for liver disease, hepatitis, or any condition, and interacts with immune-suppressive therapy.

Evidence levels describe the state of research for the traditional use discussed here, not a recommendation. Historical use does not imply effectiveness.

References & Sources

  1. PubMed · Bupleurum chinense review (2019)
  2. MSKCC · Bupleurum information (2022)

Entry last updated November 5, 2026

Soothing Brews

An educational encyclopedia preserving the history, traditions, and modern evidence behind herbs used in teas and infusions. Inspired by antique botanical manuscripts.

Steeped in tradition, grounded in honesty.

Please Note

This is an educational reference, not a medical resource. Historical use does not imply effectiveness. Natural does not always mean safe. Consult a qualified healthcare professional before using herbs, especially if pregnant, nursing, or taking medications.

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Preferred sources: NIH ODS · NCCIH · MSK Herbs · PubMed · WHO · EMA · German Commission E · Cochrane