Boneset

At a Glance

Common name

Boneset

Scientific name

Eupatorium perfoliatum

Family

Asteraceae

Region

North America

Plant part

Leaves and flowering tops

Caffeine

Caffeine Free

Evidence

Insufficient

Safety review

Safety information on file

Botanical Description

A tall native American perennial whose pairs of opposite lance-shaped leaves appear to be pierced (perfoliate) by the stout stem. Crowns of small, fuzzy white flowers bloom in late summer.

Also known as: Thoroughwort, Ague Weed, Feverwort, Sweating Plant

Historical Background

A signature remedy of 19th-century American Eclectic and Thomsonian practice for the fevers and bone-aching chills of influenza and malaria ('ague'). The name 'boneset' refers to the deep aching it was used to relieve.

Earliest recorded uses: Inducing sweating to break fevers, relieving the bone-ache of influenza, and as a bitter digestive tonic.

Cultural significance: Among the most-used Native American febrifuges adopted by settlers; long listed in the United States Pharmacopeia.

1. Indigenous

   Native American groups use boneset for fevers and colds.

2. 19th century

   A mainstay of Eclectic and Thomsonian practice for 'ague' and influenza.

3. 20th century

   Declines as quinine and modern antipyretics displace it.

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Flavor & Aroma

Aroma: Faint, pungent and hay-like

Tea Preparation

Modern Evidence

Used almost entirely on traditional grounds; controlled trials are lacking. Pharmacological interest centers on sesquiterpene lactones, but modern evidence does not establish efficacy for fever.

Evidence levels describe the state of research for the traditional use discussed here, not a recommendation. Historical use does not imply effectiveness.