Educational reference only · Not medical advice · Always consult a qualified healthcare professional
Skullcap

Scutellaria lateriflora

Skullcap

Lamiaceae

Evidence: InsufficientCaffeine Free North AmericaRelaxationSleep SupportStress
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Identity

Common Name
Skullcap
Scientific Name
Scutellaria lateriflora
Botanical Family
Lamiaceae
Native Region
North America
Cultivation Regions
North America, Europe
Plant Parts Used
Aerial parts, Leaves, Flowering tops
Synonyms
American Skullcap, Mad Dog Skullcap, Hoodwort
Caffeine Level
Caffeine Free

A slender branching square-stemmed perennial 30-80 cm tall with opposite lance-shaped toothed leaves and loose one-sided racemes of small two-lipped blue-violet flowers whose upper lip forms a hooded 'helmet' (scutella).

Historical Background

Skullcap has been a cherished nervine of North American Eclectic and Indigenous herbal traditions, used to calm tension, restlessness, and troubled sleep. The 'scutellum' helmet shape of the flower inspired the genus name and its long association with easing the mind.

Earliest recorded uses: Native American (Eclectic) and early American herbal traditions as a nervine tonic.

Traditional preparations:

  • Aerial-part infusion
  • Nervine tonic blend
  • Tincture (off-tea)

Traditional Uses

These uses document historical traditions and do not imply proven effectiveness.

Native American Traditions

Calming nervine for nervous tension, restlessness, and sleep.

Modern Herbalism

Nervine relaxant for stress and mild anxiety.

Flavor & Aroma

Mildly BitterGreenEarthySlightly Sweet

Aroma: Mild, green, slightly bitter, earthy

Tea Information

Suitable for Tea
Yes
Preparation Methods
Infusion
Steeping Temperature
200°F (93°C)
Steeping Time
10 minutes (covered)
Recommended Vessel
Covered teapot
Blends Well With
Chamomile, Lemon Balm, Passionflower, Valerian, Lavender
200°F (93°C) 10 minutes (covered)

Safety & Cautions

Contraindications
Avoid in pregnancy and liver disease. Stop before surgery. Avoid prolonged high-dose use; use only reputable, correctly identified sources.
Drug Interactions
May enhance sedative effects of CNS depressants and anesthetics; may affect liver-metabolized drugs; consult a clinician.
Pregnancy
Avoid medicinal doses.
Children
Mild infusions acceptable in small amounts; not a sedative for daily long-term use.
Allergies
Possible in those sensitive to Lamiaceae.
Known Adverse Effects
Generally well tolerated; historical liver-injury reports were mostly linked to adulteration with the toxic herb germander — use reputable sources.

Research Summary

Evidence Level: Insufficient

Skullcap has a strong folk tradition as a calming nervine for tension and sleep. Clinical evidence is insufficient; no robust trials confirm specific effects, and historical liver-injury reports were largely from adulteration. It is not a treatment for anxiety or insomnia.

Evidence levels reflect the currently available scientific literature and may change as new research emerges. Where evidence is limited or conflicting, this is stated plainly.

References & Sources

References & Sources

  1. MSKCC · Skullcap information (2022)
  2. FDA · Adverse events linked to mislabeled skullcap (germander) (2018)

Related Herbs

Soothing Brews

An educational encyclopedia preserving the history, traditions, and modern evidence behind herbs used in teas and infusions. Inspired by antique botanical manuscripts.

Steeped in tradition, grounded in honesty.

Please Note

This is an educational reference, not a medical resource. Historical use does not imply effectiveness. Natural does not always mean safe. Consult a qualified healthcare professional before using herbs, especially if pregnant, nursing, or taking medications.

© 2026 Soothing Brews · For educational purposes only.

Preferred sources: NIH ODS · NCCIH · MSK Herbs · PubMed · WHO · EMA · German Commission E · Cochrane